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Thus, dysregulation of autophagy has been shown to contribute towards the pathogenesis of many diseases, including Parkinsons disease, lysosomal storage disorders, cancer and Crohns disease 5

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REFERENCE : Tobacco leaves also contain several different alkaloid compounds, including nornicotine, neonicotine, anatabine, and myosmine, as well as polyphenols and micronutrients that naturally occur in plants